diff --git a/tox.ini b/tox.ini
index 10b144619..4e6ca3ec9 100644
--- a/tox.ini
+++ b/tox.ini
@@ -79,7 +79,7 @@ deps =
     service_identity==16.0.0
     Twisted==20.3.0
     w3lib==1.17.0
-    zope.interface==4.1.3
+    zope.interface==5.1.2
     -rtests/requirements-py3.txt
     # Extras
     botocore==1.4.87